Aging and Heart Disease

Aging and Heart Disease are interconnected in several ways. As individuals age, their chances of developing heart disease increase. Aging is associated with various physiological changes that can affect the cardiovascular system. Here are some key points to consider regarding heart disease and aging:

Atherosclerosis: Aging often leads to the accumulation of fatty deposits (plaque) in the arteries, a condition known as atherosclerosis. This buildup can narrow and stiffen the arteries, reducing blood flow to the heart and increasing the risk of heart disease.

Blood Vessel Changes: With aging, blood vessels may become less flexible and more prone to stiffness. This can contribute to high blood pressure (hypertension), which is a significant risk factor for heart disease.

Heart Muscle Changes: The heart undergoes changes with age, including a gradual thickening of the heart walls and a decrease in the elasticity of the heart chambers. These changes may affect the heart’s ability to pump blood efficiently.

Collagen Accumulation: Collagen, a protein that provides structure to various tissues, accumulates in the heart with age. This can contribute to the stiffening of the heart muscle and impaired cardiac function.

Inflammation: Chronic low-grade inflammation is associated with aging and is also a factor in the development of heart disease. Inflammatory processes can contribute to the progression of atherosclerosis and other cardiovascular issues.

Metabolic Changes: Changes in metabolism, such as alterations in lipid (fat) profiles and glucose metabolism, are common with aging. These changes can influence the development of conditions such as diabetes and metabolic syndrome, which are risk factors for heart disease.

Genetic and Environmental Factors: Both genetic and environmental factors play a role in the development of heart disease. Aging individuals may have a combination of genetic predispositions and a lifetime of exposure to various risk factors, such as a poor diet, a sedentary lifestyle, and smoking.

Hormonal Changes: Hormonal changes, especially in postmenopausal women, can contribute to an increased risk of heart disease. Estrogen, which has cardioprotective effects, decreases with age and menopause.

Lifestyle Factors: Healthy lifestyle choices, such as a balanced diet, regular physical activity, maintaining a healthy weight, and avoiding smoking, can help mitigate the risk of heart disease even as individuals age.

Medical Monitoring and Management: Regular medical check-ups and monitoring of blood pressure, cholesterol levels, and other cardiovascular risk factors are crucial, especially as people age. Timely intervention and management of risk factors can help prevent or delay the onset of heart disease.

It’s important to note that while aging is a non-modifiable risk factor, adopting a healthy lifestyle and managing other risk factors can significantly influence heart health and reduce the impact of age-related changes on the cardiovascular system. Regular consultation with healthcare professionals is essential for monitoring and managing cardiovascular health, especially in older individuals.

Pediatric Heart Infections

Pediatric heart infections, although relatively rare, can have serious and potentially life-threatening consequences for children. These infections affect the heart muscle, valves, or the inner lining of the heart chambers and are often caused by bacteria, viruses, or other microorganisms. Early detection, timely treatment, and a good understanding of the risks associated with pediatric heart infections are crucial for the well-being of affected children. In this blog, Dr. Ramji Mehrotra, India’s leading pediatric cardiac surgeon, elaborates upon the causes, symptoms, diagnosis, and treatment options for these infections.

Causes of Pediatric Heart Infections

  • Bacterial Endocarditis: This is one of the most common types of heart infections in children. It occurs when bacteria enter the bloodstream and attach to the heart valves or lining of the heart. Certain pre-existing heart conditions, congenital heart defects, or the use of intravenous (IV) lines and catheters can increase the risk of bacterial endocarditis.
  • Viral Myocarditis: Myocarditis is an inflammation of the heart muscle, often caused by viral infections such as enteroviruses or adenoviruses. While viral myocarditis is less common in children, it can lead to significant cardiac issues if left untreated.


The symptoms of pediatric heart infections can vary depending on the type and severity of the infection. Common symptoms include:

  • Fever: A persistent fever that doesn’t respond to regular treatments.
  • Fatigue: Unexplained tiredness or weakness.
  • Chest Pain: Discomfort especially during physical activity.
  • Rapid Breathing: Increased breathing rate, especially in infants.
  • Paleness: Pale or bluish skin, lips, or fingertips.
  • Joint Pain: Joint pain or swelling.
  • Swelling: Swelling in the legs and abdomen
  • Abnormal Heartbeat: Irregular heartbeat, known as arrhythmia.
  • Poor Feeding: Difficulty feeding in infants.
  • Weight Loss: Unintentional weight loss.
  • Irritability: Increased fussiness or irritability.


Diagnosing pediatric heart infections can be challenging because the symptoms can mimic those of other common childhood illnesses. Physicians typically use a combination of the following diagnostic tools:

  1. Physical Examination: A thorough physical examination to check for symptoms and signs of infection.
  2. Blood Tests: Blood tests to check for infection markers and the presence of microorganisms.
  3. Electrocardiogram (ECG or EKG): A test that records the heart’s electrical activity to identify irregularities in the heartbeat.
  4. Echocardiogram: An ultrasound of the heart to visualize its structure and function.
  5. Chest X-rays: X-rays to assess the heart and lungs.
  6. MRI or CT Scan: These imaging tests may be used to provide detailed images of the heart.


Treatment of pediatric heart infections typically involves a combination of medical therapies and, in some cases, surgical intervention, depending on the type and severity of the infection. Common treatment options include:

  1. Antibiotics: Bacterial infections are treated with antibiotics.
  2. Antiviral Medications: Viral myocarditis may be treated with antiviral drugs.
  3. Anti-inflammatory Medications: Medications like corticosteroids may be used to reduce inflammation in the heart.
  4. Surgery: In severe cases or when complications arise, surgical intervention may be necessary. This can include repairing damaged heart valves or removing infected tissue.
  5. Supportive Care: Children with heart infections may require hospitalization for supportive care, such as intravenous fluids, pain management, and monitoring of vital signs.


According to Dr. Ramji Mehrotra, pediatric heart infections are a serious concern, but with early detection and appropriate treatment, the prognosis can be favourable. Parents and healthcare providers must be vigilant about recognizing the symptoms and risk factors associated with these infections. Additionally, maintaining good hygiene practices, ensuring proper dental care, and managing pre-existing heart conditions can help reduce the risk of pediatric heart infections. Overall, a proactive approach to heart health can make a significant difference in the well-being of children.